Study on the Clinical Value of Serum Pepsinogen II in Gastritis Detection

The present study aims to explore the clinical value of pepsinogen II and gastritis detection. Firstly, serum expressions in patients with Helicobacter pylori-caused gastritis, gastric ulcer atrophic were detected using enzyme-linked immunosorbent assay, followed by statistical analysis. In comparison normal group, levels increased above groups (p<0.01). Next, positive cut-off for detecting was obtained receiver operating characteristic curve. When 10.55 μg/l, specificity sensitivity 83.6 % 74.4 diagnosis pylori-causing 81.6 80.0 53.1 gastritis. Thus, at μg/l recommended as Besides, we observed that ribonucleic acid protein different up-regulated Western blotting real-time polymerase chain reaction. Moreover, immunohistochemistry indicated highly expressed tissues compared controls. conclusion, could be an independent indicator